The MOVe-AHEAD trial will test the safety and effectiveness of an antiviral study drug for people who live with someone who has COVID-19. This clinical trial will help researchers learn whether the study drug:
There are rules in place to help protect the rights, safety, and well-being of people who volunteer for research trials. These rules are put in place to make sure trials follow strict scientific and ethical guidelines. Before a clinical research trial can begin, a review board must review the trial. This group is called an IRB or institutional review board. An IRB is made up of doctors, scientists, and members of the community.
To participate in the MOVe-AHEAD trial, you must be 18 years or older AND live with someone (adult or child) who:
Other adult members of your household may also be able to join this trial. Consider asking them if they also want to join the trial.
Below is a list of common COVID-19 signs and symptoms someone may be experiencing if they have COVID-19.
For your household to qualify for the trial, there must be at least one household member with symptoms of COVID-19 that started in the last 3 days and a positive COVID-19 test within the last 3 days. The household member with COVID-19 is called the Index Participant. If there is more than one person in your household with COVID-19, the person who developed symptoms first will be the index case. There can only be one index case in each household.
The Index Participant will be asked to join the trial for one visit, which is described below.
Since this is a prevention study, the person that already has COVID-19 will not receive treatment through this study, although they may receive treatment from their normal healthcare provider.
Any other household members who do not have COVID-19 may also be able to join the trial- this household member is called a trial patient.
Trial patients will be involved for about 1 month over 3 trial periods.
A clinical trial is a research study that tries to answer questions about how medicines work in the people who take them. Researchers run trials to test whether an investigational medication is safe and effective. These trials may help doctors find new ways to help prevent, detect, or treat health problems. Information learned from this clinical research study may help other people in the future. Additional care may also be provided for COVID-19 for those participating. This may include:
Taking part in this trial is voluntary and you may stop at any time for any reason. In addition, there is no cost for the study drug or study-related care, tests and exams.
If you would like to see if you are eligible to participate, please find a site near you.Find a site near you
If you're interested in learning more about the MOVe-AHEAD trial, including potential risks and benefits of participation, you can find additional details at CTGOV.