novel coronavirus (covid-19) study needing participants who live with someone who has covid-19

Do you live with someone who has COVID-19?

You may be able to join this trial and help doctors learn about a possible treatment to prevent illness after exposure to COVID-19. Learn more about this trial for people who have lived with someone who has COVID-19.

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Trial Overview

The MOVe-AHEAD trial will test the safety and effectiveness of an antiviral study drug for people who live with someone who has COVID-19. This clinical trial will help researchers learn whether the study drug:

What requirements are in place to help protect clinical trial participants?

There are rules in place to help protect the rights, safety, and well-being of people who volunteer for research trials. These rules are put in place to make sure trials follow strict scientific and ethical guidelines. Before a clinical research trial can begin, a review board must review the trial. This group is called an IRB or institutional review board. An IRB is made up of doctors, scientists, and members of the community.

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Who Can Join?

To participate in the MOVe-AHEAD trial, you must be 18 years or older AND live with someone (adult or child) who:

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Other adult members of your household may also be able to join this trial. Consider asking them if they also want to join the trial.

What are COVID-19 Symptoms?

Below is a list of common COVID-19 signs and symptoms someone may be experiencing if they have COVID-19.

  • Hard to Breathe
  • Fatigue
  • Cough
  • Diarrhea
  • Fever
  • Loss of Smell
  • Vomiting
  • Stuffy or Runny Nose
  • Headache
  • Chills
  • Nausea
  • Sore Throat
  • Loss of Taste
  • Muscle or Body Aches
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Ask your adult household members if they want to join the trial

For your household to qualify for the trial, there can be only 1 household member with symptoms of COVID-19 and a positive test – this household member is called the index participant. Any other adult household members who do not have COVID-19 may also be able to join this trial - this household member is called a trial patient.

What To Expect

Trial patients will be involved for about 1 month over 3 trial periods.

Screening Period

(Up to 72 Hours)

To ensure trial patients qualify, we’ll:

  • Do a Physical exam
  • Talk about their medical history

Treatment Period

(5 Days)

If they qualify and agree to take part, trial patients will be put into a group by chance to get either the antiviral study drug or placebo. A placebo looks like the study drug but does not contain any active medicine. Trial patients will:

  • Visit the trial staff for tests
  • Take the study treatment twice a day
  • Keep diaries of taking your study drug and symptoms

During the first 5 Days, trial patients may have some of the following tests:

  • Blood Pressure
  • Checkup
  • Weight
  • Respiratory Rate
  • Blood Test
  • Heart Rate
  • Temperature
  • Nasal/Throat Swab

Follow-Up Period

(After about 1 month)

After about 1 month, trial patients will:

  • Visit the study clinic up to 3 times - some visits may be at home or at an alternate location.

What to expect if you are the Index Participant

  • If you are the Index Participant you will be asked to sign consent and answer some questions about having COVID-19.
  • You may be asked to provide an oral swab test. You do not have to provide the oral swab test if you do not want to.
  • Index participants will not receive the study drug.

Why participate in this study?

A clinical trial is a research study that tries to answer questions about how medicines work in the people who take them. Researchers run trials to test whether an investigational medication is safe and effective. These trials may help doctors find new ways to help prevent, detect, or treat health problems. Information learned from this clinical research study may help other people in the future. Additional care may also be provided for COVID-19 for those participating. This may include:

  • Medical Care
  • Treatment for COVID-19 and related symptoms
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Is this mandatory?
Will it cost anything?

Taking part in this trial is voluntary and you may stop at any time for any reason. In addition, there is no cost for the study drug or study-related care, tests and exams.

United to learn more about COVID-19

If you would like to see if you are eligible to participate, please find a site near you.

Find a site near you

Where can I learn more?

If you're interested in learning more about the MOVe-AHEAD trial, including potential risks and benefits of participation, you can find additional details at CTGOV.

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